PTPN21 Antikörper (C-Term)

Produktnummer ABIN2790277

Produktdetails anti-PTPN21 Antikörper

Target: PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FWQMVWEQGI AIIAMVTAEE EGGREKSFRY WPRLGSRHNT VTYGRFKITT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PTPN21. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PTPN21

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1174 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PTPN21

Target: PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))

Andere Bezeichnung: PTPN21 (PTPN21 Produkte)

Synonyme: PTPD1 antikoerper, PTPRL10 antikoerper, Ptp2E antikoerper, protein tyrosine phosphatase, non-receptor type 21 antikoerper, PTPN21 antikoerper, Ptpn21 antikoerper

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.
Alias Symbols: PTPD1, PTPRL10
Protein Interaction Partner: KIF1C, AKAP1, TEC, BMX, SRC,
Protein Size: 1174

Molekulargewicht: 133 kDa

Gen-ID: 11099

NCBI Accession: NM_007039, NP_008970

UniProt: Q16825