PTPN21 Antikörper (AA 171-270) (Alexa Fluor 350)

Produktnummer ABIN6976841

Produktdetails anti-PTPN21 Antikörper (Alexa Fluor 350)

Target: PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))

Bindungsspezifität: AA 171-270

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN21 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PTPD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PTPN21

Target: PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))

Andere Bezeichnung: PTPD1 (PTPN21 Produkte)

Synonyme: PTPD1 antikoerper, PTPRL10 antikoerper, Ptp2E antikoerper, protein tyrosine phosphatase, non-receptor type 21 antikoerper, PTPN21 antikoerper, Ptpn21 antikoerper

Hintergrund:

Synonyms: Protein tyrosine phosphatase D1, Protein tyrosine phosphatase non receptor type 21, PTPN 21, PTPN21, PTN21_HUMAN, PTPNL, PTPRL10, Tyrosine protein phosphatase non receptor type 21.

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]

Gen-ID: 11099

UniProt: Q16825