FCGR2B Antikörper (C-Term)

Produktnummer ABIN2789536

Produktdetails anti-FCGR2B Antikörper

Target: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FCGR2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CREMGETLPE KPANPTNPDE ADKVGAENTI TYSLLMHPDA LEEPDDQNRI

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FCGR2B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 310 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FCGR2B

Target: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Andere Bezeichnung: FCGR2B (FCGR2B Produkte)

Synonyme: CD32 antikoerper, CD32B antikoerper, FCG2 antikoerper, FCGR2 antikoerper, IGFR2 antikoerper, FCGR2B antikoerper, AI528646 antikoerper, F630109E10Rik antikoerper, Fc[g]RII antikoerper, FcgRII antikoerper, Fcgr2 antikoerper, Fcgr2a antikoerper, Fcr-2 antikoerper, Fcr-3 antikoerper, Ly-17 antikoerper, Ly-m20 antikoerper, LyM-1 antikoerper, Lym-1 antikoerper, FCRII antikoerper, FcRII antikoerper, Fc fragment of IgG receptor IIb antikoerper, Fc fragment of IgG, low affinity IIb, receptor (CD32) antikoerper, Fc receptor, IgG, low affinity IIb antikoerper, low affinity immunoglobulin gamma Fc region receptor II antikoerper, FCGR2B antikoerper, Fcgr2b antikoerper, LOC100856270 antikoerper

Hintergrund: The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD32, CD32B, FCG2, FCGR2, IGFR2
Protein Interaction Partner: INPP5D, C14orf1, MAPK3, LY6E, INPPL1, BLK, MAPK1, PTPN6, LYN, CRP, APCS, SHC1, PTPN11,
Protein Size: 310

Molekulargewicht: 34 kDa

Gen-ID: 2213

NCBI Accession: NM_001002275, NP_001002275

UniProt: P31994

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling