IL1RN Antikörper (N-Term)

Produktnummer ABIN970947

Produktdetails anti-IL1RN Antikörper

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1RN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ADLYEEGGGG GGEGEDNADS KETICRPSGR KSSKMQAFRI WDVNQKTFYL

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IL1RN. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 180 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IL1RN

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Andere Bezeichnung: IL1RN (IL1RN Produkte)

Synonyme: DIRA antikoerper, ICIL-1RA antikoerper, IL-1RN antikoerper, IL-1ra antikoerper, IL-1ra3 antikoerper, IL1F3 antikoerper, IL1RA antikoerper, IRAP antikoerper, MVCD4 antikoerper, IRAP1 antikoerper, IL1RN antikoerper, IL-1RA antikoerper, F630041P17Rik antikoerper, interleukin 1 receptor antagonist antikoerper, interleukin 1 receptor antagonist-like antikoerper, IL1RN antikoerper, Il1rn antikoerper, IL1RNL antikoerper

Hintergrund: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: DIRA, ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430, MVCD4, IL-1RN, IL-1ra
Protein Interaction Partner: RELA, TERF2IP, POT1, IL1R2, IL1R1,
Protein Size: 180

Molekulargewicht: 20 kDa

Gen-ID: 3557

NCBI Accession: NM_173841, NP_776213

UniProt: Q53SC2

Pathways: NF-kappaB Signalweg, Hormone Transport, Cancer Immune Checkpoints