RAP1 Antikörper (Middle Region)
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- Target Alle RAP1 (TERF2IP) Antikörper anzeigen
- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LTYVKENARS PSSVTGNALW KAMEKSSLTQ HSWQSLKDRY LKHLRGQEHK
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Terf2ip. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product TERF2IP Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 286 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
- Andere Bezeichnung
- Terf2ip (TERF2IP Produkte)
- Synonyme
- DRIP5 antikoerper, RAP1 antikoerper, Rap1 antikoerper, cRAP1 antikoerper, TERF2 interacting protein antikoerper, telomeric repeat binding factor 2, interacting protein antikoerper, TERF2IP antikoerper, Terf2ip antikoerper
- Hintergrund
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Terf2ip acts both as a regulator of telomere function and as a transcription regulator. It is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.
Alias Symbols: Rap1
Protein Size: 286 - Molekulargewicht
- 31 kDa
- Gen-ID
- 57321
- NCBI Accession
- NM_020584, NP_065609
- UniProt
- Q91VL8
- Pathways
- Zellzyklus, Telomere Maintenance
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