PVRL2 Antikörper (Middle Region)
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- Target Alle PVRL2 Antikörper anzeigen
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PVRL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MEPDGKDEEE EEEEEKAEKG LMLPPPPALE DDMESQLDGS LISRRAVYV
- Homologie
- Human: 100%, Mouse: 93%, Pig: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PVRL2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PVRL2
- Top Product
- Discover our top product PVRL2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 479 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
- Andere Bezeichnung
- PVRL2 (PVRL2 Produkte)
- Synonyme
- prr2 antikoerper, AI325026 antikoerper, AI987993 antikoerper, Cd112 antikoerper, MPH antikoerper, Pvr antikoerper, Pvs antikoerper, nectin-2 antikoerper, CD112 antikoerper, HVEB antikoerper, PRR2 antikoerper, PVRR2 antikoerper, nectin cell adhesion molecule 2 antikoerper, Nectin2 antikoerper, NECTIN2 antikoerper
- Hintergrund
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This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD112, HVEB, PRR2, PVRR2
Protein Interaction Partner: KRTAP10-3, KRTAP10-5, KRTAP10-1, KRTAP10-7, NOTCH2NL, SIAH1, MDFI, KRTAP5-9, TIGIT, PVRL4, TNFRSF12A, PVRL3, PVRL2, LYRM4, DUS2, USP53, UBC, MAPK6, ATP5J2, PICK1, CD226, MLLT4,
Protein Size: 479 - Molekulargewicht
- 48 kDa
- Gen-ID
- 5819
- NCBI Accession
- NM_002856, NP_002847
- UniProt
- Q0MSE5
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
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