PVRL2 Antikörper (AA 251-350)
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- Target Alle PVRL2 Antikörper anzeigen
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
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Bindungsspezifität
- AA 251-350
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PVRL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Cow,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human nectin 2
- Isotyp
- IgG
- Top Product
- Discover our top product PVRL2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma." in: Translational oncology, Vol. 9, Issue 5, pp. 419-430, (2016) (PubMed).
: "
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Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma." in: Translational oncology, Vol. 9, Issue 5, pp. 419-430, (2016) (PubMed).
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- Target
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
- Andere Bezeichnung
- CD112 (PVRL2 Produkte)
- Synonyme
- prr2 antikoerper, AI325026 antikoerper, AI987993 antikoerper, Cd112 antikoerper, MPH antikoerper, Pvr antikoerper, Pvs antikoerper, nectin-2 antikoerper, CD112 antikoerper, HVEB antikoerper, PRR2 antikoerper, PVRR2 antikoerper, nectin cell adhesion molecule 2 antikoerper, Nectin2 antikoerper, NECTIN2 antikoerper
- Hintergrund
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Synonyms: HVEB, PRR2, CD112, PVRR2, Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, Poliovirus receptor-related protein 2, PVRL2
Background: Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.
- Gen-ID
- 5819
- UniProt
- Q92692
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
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