PVRL2 Antikörper (AA 58-212)

Produktnummer ABIN5611344

Produktdetails anti-PVRL2 Antikörper

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Bindungsspezifität: AA 58-212

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PVRL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CD112 (AA: extra 58-212) expressed in E. coli.

Klon: 4A11B12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu PVRL2

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Andere Bezeichnung: CD112 (PVRL2 Produkte)

Synonyme: prr2 antikoerper, AI325026 antikoerper, AI987993 antikoerper, Cd112 antikoerper, MPH antikoerper, Pvr antikoerper, Pvs antikoerper, nectin-2 antikoerper, CD112 antikoerper, HVEB antikoerper, PRR2 antikoerper, PVRR2 antikoerper, nectin cell adhesion molecule 2 antikoerper, Nectin2 antikoerper, NECTIN2 antikoerper

Hintergrund:

Description: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Aliases: NECTIN2, HVEB, PRR2, PVRL2, PVRR2

Molekulargewicht: 57.7 kDa

Gen-ID: 5819

HGNC: 5819

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization