PTPRE Antikörper (Middle Region)

Produktnummer ABIN2782718

Produktdetails anti-PTPRE Antikörper

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VILSMKRGQE YTDYINASFI DGYRQKDYFI ATQGPLAHTV EDFWRMIWEW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PTPRE. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PTPRE

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 700 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PTPRE

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Andere Bezeichnung: PTPRE (PTPRE Produkte)

Synonyme: ptpra antikoerper, HPTPE antikoerper, PTPE antikoerper, R-PTP-EPSILON antikoerper, PTPe antikoerper, PTPepsilon antikoerper, RPTPepsilon antikoerper, protein tyrosine phosphatase, receptor type E L homeolog antikoerper, protein tyrosine phosphatase, receptor type E antikoerper, protein tyrosine phosphatase, receptor type, E antikoerper, ptpre.L antikoerper, PTPRE antikoerper, Ptpre antikoerper

Hintergrund: PTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
Alias Symbols: DKFZp313F1310, HPTPE, PTPE, R-PTP-EPSILON
Protein Interaction Partner: UBC, MAPK3, MAPK1, KCNB1, KCNA5, PTPRD, PTPRS, PTPRE, SRC, YES1, FYN, GRB2,
Protein Size: 700

Molekulargewicht: 81 kDa

Gen-ID: 5791

NCBI Accession: NM_006504, NP_006495

UniProt: P23469