PTPRE Antikörper

Produktnummer ABIN7167503

Produktdetails anti-PTPRE Antikörper

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Receptor-type tyrosine-protein phosphatase epsilon protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PTPRE

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Andere Bezeichnung: PTPRE (PTPRE Produkte)

Synonyme: ptpra antikoerper, HPTPE antikoerper, PTPE antikoerper, R-PTP-EPSILON antikoerper, PTPe antikoerper, PTPepsilon antikoerper, RPTPepsilon antikoerper, protein tyrosine phosphatase, receptor type E L homeolog antikoerper, protein tyrosine phosphatase, receptor type E antikoerper, protein tyrosine phosphatase, receptor type, E antikoerper, ptpre.L antikoerper, PTPRE antikoerper, Ptpre antikoerper

Hintergrund:

Background: Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake.Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca2+.

Aliases: DKFZp313F1310 antibody, FLJ57799 antibody, FLJ58245 antibody, HPTPE antibody, Protein tyrosine phosphatase epsilon antibody, Protein tyrosine phosphatase receptor type E antibody, Protein tyrosine phosphatase receptor type epsilon antibody, Protein tyrosine phosphatase receptor type epsilon polypeptide antibody, Protein-tyrosine phosphatase epsilon antibody, PTPE antibody, Ptpre antibody, PTPRE_HUMAN antibody, R PTP Epsilon antibody, R-PTP-epsilon antibody, Receptor-type tyrosine-protein phosphatase epsilon antibody

UniProt: P23469