PTPRE Antikörper (C-Term)

Produktnummer ABIN392837

Produktdetails anti-PTPRE Antikörper

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Bindungsspezifität: AA 558-589, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PTP epsilon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-589 amino acids from the C-terminal region of human PTP epsilon.

Klon: RB0551

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-PTPRE Antikörper (ABIN392837)

Zheng, Resnick, Shalloway: "Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi." in: International journal of cancer, Vol. 122, Issue 9, pp. 1999-2007, (2008) (PubMed).

Details zu PTPRE

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Andere Bezeichnung: PTP epsilon (PTPRE Produkte)

Synonyme: ptpra antikoerper, HPTPE antikoerper, PTPE antikoerper, R-PTP-EPSILON antikoerper, PTPe antikoerper, PTPepsilon antikoerper, RPTPepsilon antikoerper, protein tyrosine phosphatase, receptor type E L homeolog antikoerper, protein tyrosine phosphatase, receptor type E antikoerper, protein tyrosine phosphatase, receptor type, E antikoerper, ptpre.L antikoerper, PTPRE antikoerper, Ptpre antikoerper

Hintergrund: PTPepsilon is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of the gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Molekulargewicht: 80642

Gen-ID: 5791

NCBI Accession: NP_006495, NP_569119

UniProt: P23469