AATF Antikörper (N-Term)
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- Target Alle AATF Antikörper anzeigen
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Rind (Kuh), Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AATF Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MAGPQPLALQ LEQLLNPRPS EADPEADPEE ATAARVIDRF DEGEDGEGDF
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against AATF. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human AATF
- Top Product
- Discover our top product AATF Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 560 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- Andere Bezeichnung
- AATF (AATF Produkte)
- Synonyme
- AATF antikoerper, ded antikoerper, che1 antikoerper, che-1 antikoerper, cb109 antikoerper, sb:cb109 antikoerper, wu:fc13d05 antikoerper, zgc:162071 antikoerper, CHE-1 antikoerper, CHE1 antikoerper, DED antikoerper, 4933415H02Rik antikoerper, 5830465M17Rik antikoerper, Che-1 antikoerper, Trb antikoerper, Ded antikoerper, apoptosis antagonizing transcription factor antikoerper, Apoptosis antagonizing transcription factor antikoerper, apoptosis antagonizing transcription factor S homeolog antikoerper, AATF antikoerper, aatf antikoerper, BFR2 antikoerper, NAEGRDRAFT_56916 antikoerper, Aatf antikoerper, aatf.S antikoerper
- Hintergrund
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The AATF is a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Alias Symbols: DED, CHE1, CHE-1
Protein Interaction Partner: MDM2, DAPK3, AR, HIPK2, NGDN, UBC, TSG101, LIN28A, MMS19, ZNF468, NEDD4L, WHSC1, SMAD3, EFNB3, CPD, UBD, CAND1, PIN1, SIRT7, SUMO2, CHEK2, RELA, tat, MAGED1, PCBD2, SS18L1, LZTR1, MPHOSPH6, POLR2J, MPP6, PAWR, DAZAP2, ATR, ATM, CHEK1, LDOC1, SP1, RB1, MAP
Protein Size: 560 - Molekulargewicht
- 63 kDa
- Gen-ID
- 26574
- NCBI Accession
- NM_012138, NP_036270
- UniProt
- Q9NY61
- Pathways
- Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom
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