AATF Antikörper (AA 1-39)

Produktnummer ABIN6971349

Produktdetails anti-AATF Antikörper

Target: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Bindungsspezifität: AA 1-39

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser AATF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: AATF/Che-1, or Apoptosis-antagonizing Transcription Factoris a key regulator of apoptosis through its interaction with MAP3K12 (DLK), as well as regulation of gene transcription and cell profileration through interaction with RNA polymerase II. AATF/Che-1 may promote cell proliferation by acting as a competitor of histone deacetylase 1 (HDAC1) interaction with the growth inhibiting protein pRb. AATF / Che-1 binding to pRb may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. AATF / Che-1 antibody (mAb) (Clone 1B2D8) was raised in a Rat host. It has been validated for use in Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against peptide comprising amino acids 1-39 of mouse AATF (Apoptosis-antagonizing transcription factor) (NP_062790).

Klon: 1B2D8

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu AATF

Target: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Andere Bezeichnung: AATF / Che-1 (AATF Produkte)

Synonyme: AATF antikoerper, ded antikoerper, che1 antikoerper, che-1 antikoerper, cb109 antikoerper, sb:cb109 antikoerper, wu:fc13d05 antikoerper, zgc:162071 antikoerper, CHE-1 antikoerper, CHE1 antikoerper, DED antikoerper, 4933415H02Rik antikoerper, 5830465M17Rik antikoerper, Che-1 antikoerper, Trb antikoerper, Ded antikoerper, apoptosis antagonizing transcription factor antikoerper, Apoptosis antagonizing transcription factor antikoerper, apoptosis antagonizing transcription factor S homeolog antikoerper, AATF antikoerper, aatf antikoerper, BFR2 antikoerper, NAEGRDRAFT_56916 antikoerper, Aatf antikoerper, aatf.S antikoerper

NCBI Accession: NP_062790

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom