IRF5 Antikörper (N-Term)

Produktnummer ABIN2780410

Produktdetails anti-IRF5 Antikörper

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Pferd, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PTPPRRVRLK PWLVAQVNSC QYPGLQWVNG EKKLFCIPWR HATRHGPSQD

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 498 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IRF5

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Andere Bezeichnung: IRF5 (IRF5 Produkte)

Synonyme: IRF5 antikoerper, irf5 antikoerper, SLEB10 antikoerper, AW491843 antikoerper, mirf5 antikoerper, im:7155364 antikoerper, zgc:76986 antikoerper, interferon regulatory factor 5 antikoerper, interferon regulatory factor 5 L homeolog antikoerper, IRF5 antikoerper, irf5 antikoerper, Irf5 antikoerper, irf5.L antikoerper

Hintergrund: IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist.
Alias Symbols: SLEB10
Protein Interaction Partner: SGTA, IRF5, COPS7B, COPS4, COPS5, COPS6, COPS8, COPS2, COPS3, UBC, GPS1, TRAF6, MYD88, RGS3, PPM1G, IRF6, HIVEP1, GRB2, CHUK, ALPI, MAVS, GTPBP2, CEP152, GTPBP1, SIN3A, NCOR2, NCOR1, KAT2B, HDAC1, EP300, CREBBP, TRIM15, IKBKE, TBK1, IRF3, XPO1,
Protein Size: 498

Molekulargewicht: 56 kDa

Gen-ID: 3663

NCBI Accession: NM_032643, NP_116032

UniProt: Q13568

Pathways: TLR Signalweg, Autophagie