PTF1A Antikörper (N-Term)

Produktnummer ABIN2780011

Produktdetails anti-PTF1A Antikörper

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTF1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FPSPYFDEED FFTDQSSRDP LEDSDELLGD EQAEVEFLSH QLHEYCYRDG

Homologie: Cow: 93%, Dog: 86%, Horse: 92%, Human: 93%, Mouse: 100%, Pig: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Ptf1a. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Ptf1a

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 324 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PTF1A

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Andere Bezeichnung: Ptf1a (PTF1A Produkte)

Synonyme: PTF1A antikoerper, PTF1 antikoerper, si:zc142h2.2 antikoerper, zgc:112216 antikoerper, Ptf1a/p48 antikoerper, XPtf1a antikoerper, PTF1-p48 antikoerper, bHLHa29 antikoerper, PTF1p48 antikoerper, pancreas specific transcription factor, 1a antikoerper, PTF1A antikoerper, ptf1a antikoerper, Ptf1a antikoerper

Hintergrund: Ptf1a is a transcriptional activator. It binds to the E-box consensus sequence 5'-CANNTG-3' and may play a role in early and late pancreas development and differentiation. Ptf1a plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates and may be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. It is required for the formation of pancreatic acinar and ductal cells. and plays an important role in cerebellar development.
Alias Symbols: PTF1-p48, PTF1p48, bHLHa29
Protein Interaction Partner: Rbpj,
Protein Size: 324

Molekulargewicht: 35 kDa

Gen-ID: 19213

NCBI Accession: NM_018809, NP_061279

UniProt: Q9QX98

Pathways: Retinoic Acid Receptor Signaling Pathway