PTF1A Antikörper (AA 224-325)

Produktnummer ABIN7162562

Produktdetails anti-PTF1A Antikörper

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Bindungsspezifität: AA 224-325

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTF1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Pancreas transcription factor 1 subunit alpha protein (224-325AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PTF1A

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Andere Bezeichnung: PTF1A (PTF1A Produkte)

Synonyme: PTF1A antikoerper, PTF1 antikoerper, si:zc142h2.2 antikoerper, zgc:112216 antikoerper, Ptf1a/p48 antikoerper, XPtf1a antikoerper, PTF1-p48 antikoerper, bHLHa29 antikoerper, PTF1p48 antikoerper, pancreas specific transcription factor, 1a antikoerper, PTF1A antikoerper, ptf1a antikoerper, Ptf1a antikoerper

Hintergrund:

Background: Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5\\\'-CANNTG-3\\\'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.

Aliases: bHLH transcription factor p48 antibody, bHLHa29 antibody, Class A basic helix-loop-helix protein 29 antibody, Class II bHLH protein PTF1A antibody, Exocrine pancreas specific transcription factor p48 antibody, p48 DNA binding subunit of transcription factor PTF1 antibody, p48 DNA-binding subunit of transcription factor PTF1 antibody, PACA antibody, PAGEN2 antibody, Pancreas specific transcription factor 1a antibody, Pancreas transcription factor 1 subunit alpha antibody, Pancreas-specific transcription factor 1a antibody, PTF 1A antibody, PTF1 p48 antibody, PTF1-p48 antibody, Ptf1a antibody, PTF1A_HUMAN antibody, PTF1P48 antibody

UniProt: Q7RTS3

Pathways: Retinoic Acid Receptor Signaling Pathway