PTF1A Antikörper (N-Term)

Produktnummer ABIN1881703

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PTF1A in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für PTF1A Antikörper (N-Term) (ABIN1881703)

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTF1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB10418

Produktdetails anti-PTF1A Antikörper

Bindungsspezifität: AA 12-43, N-Term

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Ptf1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-43 amino acids from the N-terminal region of human Ptf1a.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PTF1A Antikörper (ABIN1881703)

Yamada, Terao, Terashima, Fujiyama, Kawaguchi, Nabeshima, Hoshino: "Origin of climbing fiber neurons and their developmental dependence on Ptf1a." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 41, pp. 10924-34, (2007) (PubMed).

Details zu PTF1A

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Andere Bezeichnung: Ptf1a

Hintergrund: Ptf1a is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. This protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in the Ptf1a gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

Molekulargewicht: 34970

NCBI Accession: NP_835455

UniProt: Q7RTS3

Pathways: Retinoic Acid Receptor Signaling Pathway