TNFRSF10A Antikörper (C-Term)
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- Target Alle TNFRSF10A Antikörper anzeigen
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TNFRSF10A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RAGTAGPGDA LYAMLMKWVN KTGRNASIHT LLDALERMEE RHAKEKIQDL
- Homologie
- Human: 100%, Mouse: 80%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TNFRSF10A. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product TNFRSF10A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 468 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- Andere Bezeichnung
- TNFRSF10A (TNFRSF10A Produkte)
- Synonyme
- APO2 antikoerper, CD261 antikoerper, DR4 antikoerper, TRAILR-1 antikoerper, TRAILR1 antikoerper, TNFRSF10A antikoerper, TNF receptor superfamily member 10a antikoerper, tumor necrosis factor receptor superfamily member 26 antikoerper, tumor necrosis factor receptor superfamily, member 10a antikoerper, TNFRSF10A antikoerper, LOC510798 antikoerper
- Hintergrund
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This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Alias Symbols: APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1
Protein Interaction Partner: UBC, MARCH8, MARCH1, CFLAR, FADD, CUL3, TRAF2, CASP8, SQSTM1, TNFRSF10B, CBL, MOAP1, RASSF1, TNFRSF10D, TNFRSF10A, TNFSF10, MADD, BCL10, TRADD, RIPK1, DAP3, BTK, CD4, COL2A1, CASP10,
Protein Size: 468 - Molekulargewicht
- 50 kDa
- Gen-ID
- 8797
- NCBI Accession
- NM_003844, NP_003835
- UniProt
- O00220
- Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
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