Insulin Receptor Antikörper (Middle Region)

Produktnummer ABIN785152

Produktdetails anti-Insulin Receptor Antikörper

Target: Insulin Receptor (INSR)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Insulin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EEVSGTKGRQ ERNDIALKTN GDQASCENEL LKFSFIRTSF DKILLRWEPY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Insr. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1372 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Insulin Receptor

Target: Insulin Receptor (INSR)

Andere Bezeichnung: Insr (INSR Produkte)

Synonyme: CD220 antikoerper, HHF5 antikoerper, 4932439J01Rik antikoerper, D630014A15Rik antikoerper, IR antikoerper, IR-A antikoerper, IR-B antikoerper, 18402 antikoerper, CG18402 antikoerper, DIHR antikoerper, DILR antikoerper, DIR antikoerper, DIRH antikoerper, DIRbeta antikoerper, DInR antikoerper, DInr antikoerper, Dir-a antikoerper, Dir-b antikoerper, Dmel\\CG18402 antikoerper, INR antikoerper, INS antikoerper, Inr antikoerper, Inr-alpha antikoerper, Inr-beta antikoerper, InsR antikoerper, dINR antikoerper, dIR antikoerper, dIRH antikoerper, dInR antikoerper, dInr antikoerper, dInsR antikoerper, dinr antikoerper, dir antikoerper, er10 antikoerper, inr antikoerper, insulin/insulin-like growth factor receptor antikoerper, l(3)05545 antikoerper, l(3)93Dj antikoerper, l(3)er10 antikoerper, lnR antikoerper, ir-A antikoerper, CTK-1 antikoerper, ir antikoerper, INSR antikoerper, NV14476 antikoerper, cd220 antikoerper, hhf5 antikoerper, insulin receptor antikoerper, Insulin-like receptor antikoerper, insulin receptor L homeolog antikoerper, INSR antikoerper, Insr antikoerper, InR antikoerper, LOC100122567 antikoerper, LOC100451802 antikoerper, insr.L antikoerper

Hintergrund: This receptor binds insulin and has a tyrosine-protein kinase activity. When it is present in a hybrid receptor with IGF1R, binds IGF1.
Alias Symbols: 4932439J01Rik, CD220, D630014A15Rik, IR, IR-A, IR-B
Protein Interaction Partner: Arrb2, Src, Akt1, Jup, Irs1, Grb10, Snx9, Dok3, Sh2b2, Flot1, Dok1, Cav3, Socs1, Socs3, Sorbs1, Cav1, Pik3r1,
Protein Size: 1372

Molekulargewicht: 155 kDa

Gen-ID: 16337

NCBI Accession: NM_010568, NP_034698

UniProt: P15208

Pathways: NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity