RCHY1 Antikörper (N-Term)

Produktnummer ABIN2775660

Produktdetails anti-RCHY1 Antikörper

Target: RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Schaf, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCHY1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KLYTCRLCHD NNEDHQLDRF KVKEVQCINC EKIQHAQQTC EECSTLFGEY

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RCHY1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RCHY1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 200 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RCHY1

Target: RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))

Andere Bezeichnung: RCHY1 (RCHY1 Produkte)

Synonyme: ARNIP antikoerper, CHIMP antikoerper, PIRH2 antikoerper, PRO1996 antikoerper, RNF199 antikoerper, ZNF363 antikoerper, Pirh2 antikoerper, Zfp363 antikoerper, Znf363 antikoerper, wu:fb37e07 antikoerper, zgc:101128 antikoerper, RCHY1 antikoerper, arnip antikoerper, chimp antikoerper, pirh2 antikoerper, harnip antikoerper, rnf199 antikoerper, znf363 antikoerper, pro1996 antikoerper, ring finger and CHY zinc finger domain containing 1 antikoerper, ring finger and CHY zinc finger domain containing 1 L homeolog antikoerper, RCHY1 antikoerper, Rchy1 antikoerper, rchy1 antikoerper, rchy1.L antikoerper

Hintergrund: RCHY1 has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53.The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZNF363, hARNIP, PIRH2E, PIRH2F
Protein Interaction Partner: MEOX2, NOTCH2NL, UBASH3B, KRTAP9-2, LIMS2, SEMA4C, WDR74, ADAMTSL4, RCHY1, PGLS, KLHL41, MDM2, TAOK2, TP53, UBC, RNF2, HOXA2, YWHAE, CDK9, DCUN1D5, RILP, TMBIM1, CHD8, USP28, C19orf80, RBM38, NLK, TMEM14C, AIG1, SERTAD1, CHEK2, PRDX4, RAB11A, FADS6, TMEM1
Protein Size: 200

Molekulargewicht: 23 kDa

Gen-ID: 25898

NCBI Accession: NM_001008925, NP_001008925

UniProt: Q96PM5