RCHY1 Antikörper (AA 31-130) (Biotin)

Produktnummer ABIN1396938

Produktdetails anti-RCHY1 Antikörper (Biotin)

Target: RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))

Bindungsspezifität: AA 31-130

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCHY1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PIRH2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu RCHY1

Target: RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))

Andere Bezeichnung: PIRH2 (RCHY1 Produkte)

Synonyme: ARNIP antikoerper, CHIMP antikoerper, PIRH2 antikoerper, PRO1996 antikoerper, RNF199 antikoerper, ZNF363 antikoerper, Pirh2 antikoerper, Zfp363 antikoerper, Znf363 antikoerper, wu:fb37e07 antikoerper, zgc:101128 antikoerper, RCHY1 antikoerper, arnip antikoerper, chimp antikoerper, pirh2 antikoerper, harnip antikoerper, rnf199 antikoerper, znf363 antikoerper, pro1996 antikoerper, ring finger and CHY zinc finger domain containing 1 antikoerper, ring finger and CHY zinc finger domain containing 1 L homeolog antikoerper, RCHY1 antikoerper, Rchy1 antikoerper, rchy1 antikoerper, rchy1.L antikoerper

Hintergrund:

Synonyms: ZCHY, ARNIP, CHIMP, PIRH2, RNF199, ZNF363, PRO1996, RING finger and CHY zinc finger domain-containing protein 1, Androgen receptor N-terminal-interacting protein, CH-rich-interacting match with PLAG1, E3 ubiquitin-protein ligase Pirh2, RING finger protein 199, Zinc finger protein 363, p53-induced RING-H2 protein, hPirh2, RCHY1

Background: Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.

Gen-ID: 25898

UniProt: Q96PM5