ATG4A Antikörper (Middle Region)
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- Target Alle ATG4A Antikörper anzeigen
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATG4A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PQSLGALGGK PNNAYYFIGF LGDELIFLDP HTTQTFVDTE ENGTVNDQTF
- Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ATG4A. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ATG4A
- Top Product
- Discover our top product ATG4A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 398 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." in: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).
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Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." in: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).
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- Target
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
- Andere Bezeichnung
- ATG4A (ATG4A Produkte)
- Synonyme
- apg4a antikoerper, autl2 antikoerper, F6E13.27 antikoerper, APG4A antikoerper, zgc:111958 antikoerper, Aut2a antikoerper, AUTL2 antikoerper, AI627006 antikoerper, AV169859 antikoerper, Apg4a antikoerper, Atg4al antikoerper, Autl2 antikoerper, Atg4a antikoerper, autophagy related 4A cysteine peptidase L homeolog antikoerper, autophagy related 4A cysteine peptidase antikoerper, Peptidase family C54 protein antikoerper, ATG4 autophagy related 4 homolog A (S. cerevisiae) antikoerper, autophagy related 4A, cysteine peptidase antikoerper, atg4a.L antikoerper, ATG4A antikoerper, AT2G44140 antikoerper, atg4a antikoerper, Atg4a antikoerper
- Hintergrund
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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.
Alias Symbols: APG4A, AUTL2
Protein Interaction Partner: CDKL3, GABARAPL1, GABARAPL2, ATG101, MAP1LC3B,
Protein Size: 398 - Molekulargewicht
- 45 kDa
- Gen-ID
- 115201
- NCBI Accession
- NM_052936, NP_443168
- UniProt
- Q8WYN0
- Pathways
- Autophagie
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