Dynamitin Antikörper

Produktnummer ABIN271764

Produktdetails anti-Dynamitin Antikörper

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of p50 Dynamitin protein. (region surrounding Leu371)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Dynamitin

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Andere Bezeichnung: Dynactin Subunit 2 (DCTN2 Produkte)

Synonyme: DCTN2 antikoerper, dctn2 antikoerper, dctn50 antikoerper, dynamitin antikoerper, rbp50 antikoerper, CG8269 antikoerper, DMN antikoerper, Dmel\\CG8269 antikoerper, P50 antikoerper, dDyn antikoerper, dmn antikoerper, dyna antikoerper, l(2)k16109 antikoerper, l(2)k16218 antikoerper, p50 antikoerper, p50/Dmn antikoerper, p50/dynamitin antikoerper, 2310042E05Rik antikoerper, C130077D06Rik antikoerper, C87049 antikoerper, DCTN-50 antikoerper, GMP23-48K antikoerper, RBP50 antikoerper, DCTN50 antikoerper, DYNAMITIN antikoerper, zgc:63867 antikoerper, dynactin subunit 2 antikoerper, dynactin subunit 2 S homeolog antikoerper, Dynactin 2, p50 subunit antikoerper, dynactin 2 antikoerper, dynactin 2 (p50) antikoerper, dynactin subunit 2 L homeolog antikoerper, DCTN2 antikoerper, dctn2.S antikoerper, DCTN2-p50 antikoerper, dctn2 antikoerper, Dctn2 antikoerper, dctn2.L antikoerper

Hintergrund: Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This , is against the full length p50 dynamitin.Synonyms: 50 kDa dynein-associated polypeptide, DCTN2, DCTN50, Dynactin 2, Dynactin complex 50 kDa subunit, RBP50, p50 dynamitin

Molekulargewicht: approx. 44 kDa

Gen-ID: 10540

NCBI Accession: NP_006391

UniProt: Q13561

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization