Dynamitin Produkte
(Dynactin 2 (p50) (DCTN2))
Kategorien
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012].
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Ausgewählte Dynamitin Kategorien
Dynamitin Antikörper
High quality antibodies with extensive validation data.
Dynamitin ELISA Kits
Reliable ELISA kits for a wide range of species.
Dynamitin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Dynamitin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7260303
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN523956
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (4)
Kat. Nr.
ABIN564596
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Dynamitin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381385
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4882620
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6386396
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Dynamitin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122716
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351222
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351224
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Dynamitin Produkten
: "Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls." in: Aging cell, Vol. 15, Issue 5, pp. 924-39, (2016) (PubMed).: "Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum." in: Scientific reports, Vol. 5, pp. 8389, (2015) (PubMed).
: "Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5." in: The Biochemical journal, Vol. 463, Issue 3, pp. 339-49, (2014) (PubMed).
: "Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling." in: Oncogene, Vol. 21, Issue 13, pp. 1945-54, (2002) (PubMed).
: "beta III spectrin binds to the Arp1 subunit of dynactin." in: The Journal of biological chemistry, Vol. 276, Issue 39, pp. 36598-605, (2001) (PubMed).
: "ZW10 helps recruit dynactin and dynein to the kinetochore." in: The Journal of cell biology, Vol. 142, Issue 3, pp. 763-74, (1998) (PubMed).
: "Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution." in: The Journal of cell biology, Vol. 139, Issue 2, pp. 469-84, (1997) (PubMed).
: "Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis." in: The Journal of cell biology, Vol. 132, Issue 4, pp. 617-33, (1996) (PubMed).
Synonyme und alternative Namen zu Dynamitin
dynactin subunit 2 (DCTN2), dynactin subunit 2 S homeolog (dctn2.S), Dynactin 2, p50 subunit (DCTN2-p50), dynactin subunit 2 (dctn2), dynactin 2 (Dctn2), dynactin subunit 2 (Dctn2), dynactin 2 (p50) (dctn2), dynactin subunit 2 L homeolog (dctn2.L), 2310042E05Rik, C87049, C130077D06Rik, CG8269, DCTN-50, DCTN2, dctn2, dctn50, DCTN50, dDyn, Dmel\\CG8269, DMN, dmn, dyna, dynamitin, DYNAMITIN, GMP23-48K, l(2)k16109, l(2)k16218, P50, p50, p50/Dmn, p50/dynamitin, rbp50, RBP50, zgc:63867Bezeichner auf Proteinebene für Dynamitin
- dynactin 2 (p50)
- dynactin subunit 2
- dynactin subunit 2-B
- dynamitin
- CG8269-PA
- Dmn-PA
- p50-dynamitin
- p50 dynamitin
- p50/Dynamitin
- 50 kDa dynein-associated polypeptide
- dynactin complex 50 kDa subunit
- growth cone membrane protein 23-48K
- 50 kD dynein-associated polypeptide
- dynactin complex 50 kD subunit
- p50/dynamitin
- dynactin subunit 2-A
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