Dynamitin Protein (AA 1-406) (His tag)
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- Target Alle Dynamitin (DCTN2) Proteine anzeigen
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-406
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Dynamitin Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MGSSHHHHHH SSGLVPRGSH MGSMADPKYA DLPGIARNEP DVYETSDLPE DDQAEFDAFA QELEELTSTS VEHIIVNPNA AYDKFKDKRV GTKGLDFSDR IGKTKRTGYE SGEYEMLGEG LGVKETPQQK YQRLLHEVQE LTTEVEKIKT TVKESATEEK LTPVLLAKQL AALKQQLVAS HLEKLLGPDA AINLTDPDGA LAKRLLLQLE ATKNSKGGSG GKTTGTPPDS SLVTYELHSR PEQDKFSQAA KVAELEKRLT ELETAVRCDQ DAQNPLSAGL QGACLMETVE LLQAKVSALD LAVLDQVEAR LQSVLGKVNE IAKHKASVED ADTQSKVHQL YETIQRWSPI ASTLPELVQR LVTIKQLHEQ AMQFGQLLTH LDTTQQMIAN SLKDNTTLLT QVQTTMRENL ATVEGNFASI DERMKKLGK
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DCTN2 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl( pH 8.0) containing 20 % glycerol, 0.15M NaCl, 1 mM DTT
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
- Andere Bezeichnung
- DCTN2 (DCTN2 Produkte)
- Synonyme
- DCTN2 Protein, dctn2 Protein, dctn50 Protein, dynamitin Protein, rbp50 Protein, CG8269 Protein, DMN Protein, Dmel\\CG8269 Protein, P50 Protein, dDyn Protein, dmn Protein, dyna Protein, l(2)k16109 Protein, l(2)k16218 Protein, p50 Protein, p50/Dmn Protein, p50/dynamitin Protein, 2310042E05Rik Protein, C130077D06Rik Protein, C87049 Protein, DCTN-50 Protein, GMP23-48K Protein, RBP50 Protein, DCTN50 Protein, DYNAMITIN Protein, zgc:63867 Protein, dynactin subunit 2 Protein, dynactin subunit 2 S homeolog Protein, Dynactin 2, p50 subunit Protein, dynactin 2 Protein, dynactin 2 (p50) Protein, dynactin subunit 2 L homeolog Protein, DCTN2 Protein, dctn2.S Protein, DCTN2-p50 Protein, dctn2 Protein, Dctn2 Protein, dctn2.L Protein
- Hintergrund
- DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Recombinant human DCTN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 47.2kDa (429aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_006391
- UniProt
- Q13561
- Pathways
- M Phase, Ribonucleoprotein Complex Subunit Organization
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