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CD22 Antikörper

CD22 Reaktivität: Human FACS, IHC (fro) Wirt: Maus Monoclonal HIB22 unconjugated
Produktnummer ABIN2689094
  • Target Alle CD22 Antikörper anzeigen
    CD22 (CD22 Molecule (CD22))
    Reaktivität
    • 153
    • 50
    • 24
    • 5
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 101
    • 61
    • 14
    Maus
    Klonalität
    • 124
    • 54
    Monoklonal
    Konjugat
    • 81
    • 15
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD22 Antikörper ist unkonjugiert
    Applikation
    • 111
    • 71
    • 45
    • 38
    • 38
    • 18
    • 13
    • 11
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Marke
    BD Pharmingen™
    Produktmerkmale
    Reacts with the 130-140 kDa glycosylated type I integral membrane protein present on the surface of mature B cells. CD22 is expressed in the cytoplasm of virtually all B cells except plasma cells. CD45RO antigen on T cells and CD75 antigen on B cells have been identified as ligands for CD22. CD22 has been reported to participate in B-cell activation and also as an adhesion molecule. Although the immunobiology of this antigen has not been fully elucidated, reports indicate that ligation of CD22 induces constitutive internalization of the molecule followed by complete degradation. Profile of peripheral blood lymphocytes analyzed on a BD FACScan™ .

    BD Pharmingen™ Purified Mouse Anti-Human CD22 - Purified - Clone HIB22 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Klon
    HIB22
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD22 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Shan, Press: "Constitutive endocytosis and degradation of CD22 by human B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 9, pp. 4466-75, (1995) (PubMed).

    Clark: "CD22, a B cell-specific receptor, mediates adhesion and signal transduction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 11, pp. 4715-8, (1993) (PubMed).

  • Target
    CD22 (CD22 Molecule (CD22))
    Andere Bezeichnung
    CD22 (CD22 Produkte)
    Synonyme
    A530093D23 antikoerper, Lyb-8 antikoerper, Lyb8 antikoerper, SIGLEC-2 antikoerper, SIGLEC2 antikoerper, siglec-2 antikoerper, CD22 antigen antikoerper, CD22 molecule antikoerper, Cd22 antikoerper, CD22 antikoerper
    Hintergrund
    Synonyms: BL-CAM
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