TIM3 Antikörper

Produktnummer ABIN2664624

Produktdetails anti-TIM3 Antikörper

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TIM3 Antikörper ist unkonjugiert

Applikation: ELISpot (Detection) (ELISPOT (Detection)), ELISA (Detection)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: RMT3-23

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Andere Bezeichnung: CD366 (TIM 3 Produkte)

Synonyme: HAVCR2 antikoerper, MGC140131 antikoerper, HAVcr-2 antikoerper, KIM-3 antikoerper, TIM3 antikoerper, TIMD-3 antikoerper, TIMD3 antikoerper, Tim-3 antikoerper, TIM-3 antikoerper, Tim3 antikoerper, Timd3 antikoerper, tim3 antikoerper, hepatitis A virus cellular receptor 2 antikoerper, HAVCR2 antikoerper, Havcr2 antikoerper

Substanzklasse: Virus

Hintergrund: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b+ macrophages. Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints