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KIT Antikörper (PE)
KIT
Reaktivität: Human
FACS, ICFC
Wirt: Maus
Monoclonal
A3C6E2
PE
Produktnummer ABIN2662956
Produktdetails anti-KIT Antikörper (PE)
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Target
Alle KIT Antikörper anzeigen
KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
Reaktivität
Alle Reaktivitäten für KIT Antikörper
Human
Wirt
Alle Wirte für KIT Antikörper
Maus
Klonalität
Alle Klonalitäten für KIT Antikörper
Monoklonal
Konjugat
Alle Konjugate für KIT Antikörper
Dieser KIT Antikörper ist konjugiert mit PE
Applikation
Alle Applikationen für KIT Antikörper
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Klon
A3C6E2
Isotyp
IgG1 kappa
Top Product
Discover our top product KIT Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Protect from prolonged exposure to light. Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu KIT
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Target
KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
Andere Bezeichnung
CD117 (KIT Produkte )
Synonyme
C-Kit antikoerper, CD117 antikoerper, PBT antikoerper, SCFR antikoerper, Bs antikoerper, Fdc antikoerper, Gsfsco1 antikoerper, Gsfsco5 antikoerper, Gsfsow3 antikoerper, SCO1 antikoerper, SCO5 antikoerper, SOW3 antikoerper, Ssm antikoerper, Tr-kit antikoerper, W antikoerper, c-KIT antikoerper, c-kit antikoerper, MGF antikoerper, KIT antikoerper, C-KIT antikoerper, kit antikoerper, receptor antikoerper, sparse antikoerper, Xkl-1 antikoerper, kit-a antikoerper, kit-b antikoerper, kl1-A antikoerper, krk1 antikoerper, pbt antikoerper, scfr antikoerper, KIT proto-oncogene receptor tyrosine kinase antikoerper, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antikoerper, KIT proto-oncogene receptor tyrosine kinase S homeolog antikoerper, KIT antikoerper, Kit antikoerper, kita antikoerper, kit antikoerper, kit.S antikoerper
Hintergrund
CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4 % bone marrow cells), mast cells, and acute myeloid leukemic cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117, and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells. The A3C6E2 antibody potently blocks the binding of SCF.
Pathways
RTK Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Sensory Perception of Sound , Stem Cell Maintenance , Production of Molecular Mediator of Immune Response , Regulation of long-term Neuronal Synaptic Plasticity
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