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PD-1 Antikörper (FITC)

PDCD1 Reaktivität: Human FACS Wirt: Maus Monoclonal EH12-2H7 FITC
Produktnummer ABIN2661634
  • Target Alle PD-1 (PDCD1) Antikörper anzeigen
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Reaktivität
    • 157
    • 89
    • 25
    • 5
    • 3
    • 1
    Human
    Wirt
    • 82
    • 77
    • 36
    • 13
    • 12
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 160
    • 62
    • 2
    Monoklonal
    Konjugat
    • 100
    • 18
    • 14
    • 14
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PD-1 Antikörper ist konjugiert mit FITC
    Applikation
    • 143
    • 61
    • 45
    • 42
    • 37
    • 19
    • 13
    • 13
    • 13
    • 10
    • 10
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Kreuzreaktivität
    Schimpanse, Marmoset, Rhesusaffen, Squirrel Monkey (Saimiri spec.), Cynomolgus
    Aufreinigung
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Klon
    EH12-2H7
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product PDCD1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from prolonged exposure to light. Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Andere Bezeichnung
    CD279 (PDCD1 Produkte)
    Synonyme
    CD279 antikoerper, PD-1 antikoerper, PD1 antikoerper, SLEB2 antikoerper, hPD-1 antikoerper, hPD-l antikoerper, Ly101 antikoerper, Pdc1 antikoerper, programmed cell death 1 antikoerper, PDCD1 antikoerper, Pdcd1 antikoerper
    Hintergrund
    Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
    Pathways
    Cancer Immune Checkpoints
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