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TNFRSF10B Antikörper (Biotin)
TNFRSF10B
Reaktivität: Maus
WB, IHC, ICFC, ELISA (Capture)
Wirt: Hamster
Monoclonal
MD5-1
Biotin
Produktnummer ABIN2661014
Produktdetails anti-TNFRSF10B Antikörper (Biotin)
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Target
Alle TNFRSF10B Antikörper anzeigen
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Reaktivität
Alle Reaktivitäten für TNFRSF10B Antikörper
Maus
Wirt
Alle Wirte für TNFRSF10B Antikörper
Hamster
Klonalität
Alle Klonalitäten für TNFRSF10B Antikörper
Monoklonal
Konjugat
Alle Konjugate für TNFRSF10B Antikörper
Dieser TNFRSF10B Antikörper ist konjugiert mit Biotin
Applikation
Alle Applikationen für TNFRSF10B Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Intracellular Flow Cytometry (ICFC), ELISA (Capture)
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Klon
MD5-1
Isotyp
IgG
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Discover our top product TNFRSF10B Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu TNFRSF10B
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Target
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Andere Bezeichnung
CD262 (TNFRSF10B Produkte )
Synonyme
TNFRSF10B antikoerper, dr5 antikoerper, cd262 antikoerper, killer antikoerper, trick2 antikoerper, trickb antikoerper, xDR-M1 antikoerper, xDR-M2 antikoerper, ztnfr9 antikoerper, trailr2 antikoerper, trick2a antikoerper, trick2b antikoerper, CD262 antikoerper, DR5 antikoerper, KILLER antikoerper, KILLER/DR5 antikoerper, TRAIL-R2 antikoerper, TRAILR2 antikoerper, TRICK2 antikoerper, TRICK2A antikoerper, TRICK2B antikoerper, TRICKB antikoerper, ZTNFR9 antikoerper, Ly98 antikoerper, MK antikoerper, tumor necrosis factor receptor superfamily, member 10b antikoerper, tumor necrosis factor receptor superfamily member 10b S homeolog antikoerper, tumor necrosis factor receptor superfamily member 10b L homeolog antikoerper, tumor necrosis factor receptor superfamily member 10b antikoerper, TNF receptor superfamily member 10b antikoerper, Tnfrsf10b antikoerper, TNFRSF10B antikoerper, tnfrsf10b.S antikoerper, tnfrsf10b.L antikoerper, tnfrsf10b antikoerper
Hintergrund
CD262 is a 55 kD protein also known as DR5, TRAIL-R2, Apo-2, TRICK2, and KILLER. DR5 is member 10B of the TNF receptor superfamily (TNFRSF10B), widely expressed in normal tissues and some tumor cell lines. The DR5 receptor binds to TRAIL and interacts with the cytoplasmic proteins TRADD and RIP. TRAIL binding to DR5 activates NF- κB and induces apoptosis. DR5 is induced by wild-type p53.
Pathways
p53 Signalweg , Apoptose , Positive Regulation of Endopeptidase Activity
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