SIRPA Antikörper (PE/Dazzle™ 594)

Produktnummer ABIN2659659

Produktdetails anti-SIRPA Antikörper (PE/Dazzle™ 594)

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser SIRPA Antikörper ist konjugiert mit PE/Dazzle™ 594

Applikation: Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions. The solution is free of unconjugated PE/Dazzle™ 594 and unconjugated antibody.

Klon: P84

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu SIRPA

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Andere Bezeichnung: CD172a (SIRPA Produkte)

Synonyme: BIT antikoerper, CD172A antikoerper, MFR antikoerper, MYD-1 antikoerper, P84 antikoerper, PTPNS1 antikoerper, SHPS1 antikoerper, SIRP antikoerper, SIRPA antikoerper, SIRP-A1 antikoerper, SIRP-B1 antikoerper, AI835480 antikoerper, Bit antikoerper, CD172a antikoerper, Ptpns1 antikoerper, SHP-1 antikoerper, SHPS-1 antikoerper, swc3 antikoerper, signal regulatory protein alpha antikoerper, myeloperoxidase antikoerper, signal-regulatory protein alpha antikoerper, tyrosine-protein phosphatase non-receptor type substrate 1 antikoerper, SIRPA antikoerper, MPO antikoerper, LOC458039 antikoerper, LOC100400378 antikoerper, LOC100590224 antikoerper, Sirpa antikoerper

Hintergrund: CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.