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SIRPA Produkte

(Signal-Regulatory Protein alpha (SIRPA))

Kategorien

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq, Jul 2008].

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Ausgewählte SIRPA Kategorien

SIRPA Antikörper

High quality antibodies with extensive validation data.

SIRPA ELISA Kits

Reliable ELISA kits for a wide range of species.

SIRPA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SIRPA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS, ELISA, IHC, ICC, Neut
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN5611267
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (5)
Kat. Nr. ABIN530824
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, ELISA, IP, IF
Validierungen
  • (4)
Kat. Nr. ABIN6961045
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SIRPA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970225
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962326
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959481
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SIRPA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (8)
Kat. Nr. ABIN7275652
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7275654
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7275650
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SIRPA Produkten

Andrejeva, Capoccia, Hiebsch, Donio, Darwech, Puro, Pereira: "Novel SIRPα Antibodies That Induce Single-Agent Phagocytosis of Tumor Cells while Preserving T Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 206, Issue 4, pp. 712-721, (2021) (PubMed).

Li, Gu, Rao, Lu, Wen, Chen, Wang, Cui, Tang, Xu, Wang, Yu, Ge: "Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation." in: Translational oncology, Vol. 14, Issue 8, pp. 101129, (2021) (PubMed).

Deuse, Hu, Agbor-Enoh, Jang, Alawi, Saygi, Gravina, Tediashvili, Nguyen, Liu, Valantine, Lanier, Schrepfer: "The SIRPα-CD47 immune checkpoint in NK cells." in: The Journal of experimental medicine, Vol. 218, Issue 3, (2021) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Sarute, Ibrahim, Medegan Fagla, Lavanya, Cuevas, Stavrou, Otkiran-Clare, Tyynismaa, Henao-Mejia, Ross: "TRIM2, a novel member of the antiviral family, limits New World arenavirus entry." in: PLoS biology, Vol. 17, Issue 2, pp. e3000137, (2019) (PubMed).

Yu, Qiu, Long, Yang, Zhang, Xu, Chang, Du, Hou, Yu, Zeng, Wang, Sun: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).

Londino, Gulick, Isenberg, Mallampalli: "Cleavage of Signal Regulatory Protein α (SIRPα) Enhances Inflammatory Signaling." in: The Journal of biological chemistry, Vol. 290, Issue 52, pp. 31113-25, (2015) (PubMed).

Jiang, Zhang, Gao, Zong, Zhou, Liu, Zhang, Bian, Zhu, Fan, Zhang, Li: "Signal regulatory protein-α protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signaling." in: Hypertension (Dallas, Tex. : 1979), Vol. 63, Issue 1, pp. 96-104, (2013) (PubMed).

Price, Hope: "Enhanced secretion of interferon-gamma by bovine gammadelta T cells induced by coculture with Mycobacterium bovis-infected dendritic cells: evidence for reciprocal activating signals." in: Immunology, Vol. 126, Issue 2, pp. 201-8, (2009) (PubMed).

Waters, Palmer, Nonnecke, Thacker, Estes, Larsen, Jacobs, Andersen, McNair, Minion, Lyashchenko, Hewinson, Vordermeier, Sacco: "Signal regulatory protein alpha (SIRPalpha) cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria." in: PLoS ONE, Vol. 4, Issue 7, pp. e6414, (2009) (PubMed).

Synonyme und alternative Namen zu SIRPA

signal regulatory protein alpha (SIRPA), myeloperoxidase (MPO), signal-regulatory protein alpha (SIRPA), tyrosine-protein phosphatase non-receptor type substrate 1 (LOC458039), tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100400378), tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100590224), signal-regulatory protein alpha (Sirpa), AI835480, BIT, Bit, CD172A, CD172a, MFR, MYD-1, P84, PTPNS1, Ptpns1, SHP-1, SHPS-1, SHPS1, SIRP, SIRP-A1, SIRP-B1, SIRPA, swc3

Bezeichner auf Proteinebene für SIRPA

  • CD172 antigen-like family member A
  • brain-immunoglobulin-like molecule with tyrosine-based activation motifs
  • inhibitory receptor SHPS-1
  • macrophage fusion receptor
  • myd-1 antigen
  • tyrosine phosphatase SHP substrate 1
  • tyrosine-protein phosphatase non-receptor type substrate 1
  • MyD-1 antigen
  • SHP substrate 1
  • SHPS-1
  • protein tyrosine phosphatase, non-receptor type substrate 1
  • signal-regulatory protein alpha-1
  • sirp-alpha-1
  • signal-regulatory protein alpha
  • signal regulatory protein alpha
  • tyrosine-protein phosphatase non-receptor type substrate 1-like
  • brain Ig-like molecule with tyrosine-based activation motifs
  • brain immunological-like with tyrosine-based motifs
  • mSIRP-alpha1
  • myD-1 antigen
  • Brain immunoglobulin like protein with tyrosine - based activation motifs
  • Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1)
  • Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1)
  • macrophage membrane protein MFP150
  • swine workshop cluster 3 antigen
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