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SIRPA Produkte

(Signal-Regulatory Protein alpha, SIRPA)

Kategorien

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq, Jul 2008].

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Ausgewählte SIRPA Kategorien

SIRPA Antikörper

High quality antibodies with extensive validation data.

SIRPA ELISA Kits

Reliable ELISA kits for a wide range of species.

SIRPA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SIRPA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
ApplikationELISA, FACS, WB
Validierungen
  • (1)
  • collections(4)
Kat. Nr.ABIN5611267
Menge0.1 mg
ReaktivitätHuman
ApplikationIF, ELISA, WB
Validierungen
  • collections(5)
Kat. Nr.ABIN530824
Menge100 μg
ReaktivitätHuman
ApplikationELISA, FACS, IF, IP
Validierungen
  • collections(4)
Kat. Nr.ABIN6961045
Menge100 μL

Empfohlene SIRPA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
  • collections(1)
Kat. Nr.ABIN6959481
Menge96 tests
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
  • collections(1)
Kat. Nr.ABIN6962326
Menge96 tests
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
  • collections(1)
Kat. Nr.ABIN6973559
Menge96 tests

Empfohlene SIRPA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
SourceHEK-293 Cells
Validierungen
  • collections(4)
Kat. Nr.ABIN6961082
Menge100 μg
ReaktivitätCynomolgus
SourceHEK-293 Cells
Validierungen
  • (1)
  • collections(3)
Kat. Nr.ABIN6253574
Menge100 μg
ReaktivitätHuman
SourceHEK-293 Cells
Validierungen
  • (3)
  • collections(2)
Kat. Nr.ABIN2181765
Menge100 μg

Neueste Publikationen zu unseren SIRPA Produkten

Andrejeva, Capoccia, Hiebsch, Donio, Darwech, Puro, Pereira: "Novel SIRPα Antibodies That Induce Single-Agent Phagocytosis of Tumor Cells while Preserving T Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 206, Issue 4, pp. 712-721, 2021 (PubMed).

Li, Gu, Rao, Lu, Wen, Chen, Wang, Cui, Tang, Xu, Wang, Yu, Ge: "Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation." in: Translational oncology, Vol. 14, Issue 8, pp. 101129, 2021 (PubMed).

Deuse, Hu, Agbor-Enoh, Jang, Alawi, Saygi, Gravina, Tediashvili, Nguyen, Liu, Valantine, Lanier, Schrepfer: "The SIRPα-CD47 immune checkpoint in NK cells." in: The Journal of experimental medicine, Vol. 218, Issue 3, 2021 (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, 2020 (PubMed).

Sarute, Ibrahim, Medegan Fagla, Lavanya, Cuevas, Stavrou, Otkiran-Clare, Tyynismaa, Henao-Mejia, Ross: "TRIM2, a novel member of the antiviral family, limits New World arenavirus entry." in: PLoS biology, Vol. 17, Issue 2, pp. e3000137, 2019 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Yu, Qiu, Long, Yang, Zhang, Xu, Chang, Du, Hou, Yu, Zeng, Wang, Sun: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, 2018 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS)

Londino, Gulick, Isenberg, Mallampalli: "Cleavage of Signal Regulatory Protein α (SIRPα) Enhances Inflammatory Signaling." in: The Journal of biological chemistry, Vol. 290, Issue 52, pp. 31113-25, 2015 (PubMed).

Jiang, Zhang, Gao, Zong, Zhou, Liu, Zhang, Bian, Zhu, Fan, Zhang, Li: "Signal regulatory protein-α protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signaling." in: Hypertension (Dallas, Tex. : 1979), Vol. 63, Issue 1, pp. 96-104, 2013 (PubMed).

Price, Hope: "Enhanced secretion of interferon-gamma by bovine gammadelta T cells induced by coculture with Mycobacterium bovis-infected dendritic cells: evidence for reciprocal activating signals." in: Immunology, Vol. 126, Issue 2, pp. 201-8, 2009 (PubMed).

Waters, Palmer, Nonnecke, Thacker, Estes, Larsen, Jacobs, Andersen, McNair, Minion, Lyashchenko, Hewinson, Vordermeier, Sacco: "Signal regulatory protein alpha (SIRPalpha) cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria." in: PLoS ONE, Vol. 4, Issue 7, pp. e6414, 2009 (PubMed).

Synonyme und alternative Namen zu SIRPA

signal regulatory protein alpha (SIRPA), myeloperoxidase (MPO), signal-regulatory protein alpha (SIRPA), tyrosine-protein phosphatase non-receptor type substrate 1 (LOC458039), tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100400378), tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100590224), signal-regulatory protein alpha (Sirpa), AI835480, BIT, Bit, CD172A, CD172a, MFR, MYD-1, P84, Ptpns1, PTPNS1, SHP-1, SHPS-1, SHPS1, SIRP, SIRP-A1, SIRP-B1, SIRPA, swc3

Gen-IDs für verschiedene Spezies

GENE ID SPEZIES
140885 Homo sapiens
4353 Homo sapiens
327666 Bos taurus
419267 Gallus gallus
458039 Pan troglodytes
609452 Canis lupus familiaris
717811 Macaca mulatta
100067339 Equus caballus
100351485 Oryctolagus cuniculus
100400378 Callithrix jacchus
100456232 Pongo abelii
100590224 Nomascus leucogenys
19261 Mus musculus
25528 Rattus norvegicus
494566 Sus scrofa

Bezeichner auf Proteinebene für SIRPA

  • CD172 antigen-like family member A
  • brain-immunoglobulin-like molecule with tyrosine-based activation motifs
  • inhibitory receptor SHPS-1
  • macrophage fusion receptor
  • myd-1 antigen
  • tyrosine phosphatase SHP substrate 1
  • tyrosine-protein phosphatase non-receptor type substrate 1
  • MyD-1 antigen
  • SHP substrate 1
  • SHPS-1
  • protein tyrosine phosphatase, non-receptor type substrate 1
  • signal-regulatory protein alpha-1
  • sirp-alpha-1
  • signal-regulatory protein alpha
  • signal regulatory protein alpha
  • tyrosine-protein phosphatase non-receptor type substrate 1-like
  • brain Ig-like molecule with tyrosine-based activation motifs
  • brain immunological-like with tyrosine-based motifs
  • mSIRP-alpha1
  • myD-1 antigen
  • Brain immunoglobulin like protein with tyrosine - based activation motifs
  • Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1)
  • Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1)
  • macrophage membrane protein MFP150
  • swine workshop cluster 3 antigen
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