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SIRT1 Produkte

(Sirtuin 1 (SIRT1))
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008].

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Ausgewählte SIRT1 Kategorien

SIRT1 Antikörper

High quality antibodies with extensive validation data.

SIRT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIRT1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SIRT1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (5)
  • (7)
Kat. Nr. ABIN729853
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (3)
  • (5)
Kat. Nr. ABIN565071
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, IF
Validierungen
  • (9)
Kat. Nr. ABIN6147784
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SIRT1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (8)
  • (1)
Kat. Nr. ABIN6959485
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN6959487
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970229
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SIRT1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125104
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320039
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3095388
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SIRT1 Produkten

Balaha, Alamer, Eisa, Aljohani: "Shikonin Alleviates Gentamicin-Induced Renal Injury in Rats by Targeting Renal Endocytosis, SIRT1/Nrf2/HO-1, TLR-4/NF-κB/MAPK, and PI3K/Akt Cascades." in: Antibiotics (Basel, Switzerland), Vol. 12, Issue 5, (2023) (PubMed).

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Ar Rochmah, Harini, Septyaningtrias, Sari, Susilowati: "Centella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor-α Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of Chronic Stress." in: BioMed research international, Vol. 2019, pp. 2649281, (2019) (PubMed).

Hou, Su, Chen, Niu, Zhao, Wang, Shen: "Association of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population." in: Hepatology international, Vol. 12, Issue 1, pp. 56-66, (2018) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Synonyme und alternative Namen zu SIRT1

sirtuin 1 (SIRT1), sirtuin 1 (SRT1), sirtuin 1 (Sirt1), sirtuin 1 L homeolog (sirt1.L), AA673258, Sir2, SIR2, Sir2a, Sir2alpha, SIR2L1, sir2l1, sirtuin, sirtuin 1

Bezeichner auf Proteinebene für SIRT1

  • sirtuin 1
  • NAD-dependent deacetylase sirtuin-1
  • NAD-dependent protein deacetylase sirtuin-1
  • SIR2-like protein 1
  • mSIR2a
  • regulatory protein SIR2 homolog 1
  • sir2-like 1
  • sirtuin 1 ((silent mating type information regulation 2, homolog) 1
  • SIR2alpha
  • hSIR2
  • hSIRT1
  • sirtuin type 1
  • sirtuin (silent mating type information regulation 2 homolog) 1
  • NAD-dependent deacetylase sirtuin 1
  • sirtuin1
  • Sir2alpha
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