SIRT6 Produkte
(Sirtuin 6 (SIRT6))
Kategorien
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010].
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Ausgewählte SIRT6 Kategorien
SIRT6 Antikörper
High quality antibodies with extensive validation data.
SIRT6 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIRT6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SIRT6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7437191
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, ICC, FACS
Validierungen
- (5)
Kat. Nr.
ABIN5542442
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Mouse, Rat
Applikation
WB, IP, IF
Validierungen
- (3)
Kat. Nr.
ABIN6241508
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SIRT6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959496
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959497
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN5593053
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SIRT6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1320053
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125110
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1320054
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SIRT6 Produkten
: "Protective effects of SIRT6 against lipopolysaccharide (LPS) are mediated by deacetylation of Ku70." in: Molecular immunology, Vol. 101, pp. 312-318, (2019) (PubMed).: "SIRT6 Depletion Sensitizes Human Hepatoma Cells to Chemotherapeutics by Downregulating MDR1 Expression." in: Frontiers in pharmacology, Vol. 9, pp. 194, (2018) (PubMed).
: "SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability." in: Nature communications, Vol. 7, pp. 12235, (2018) (PubMed).
: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." in: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).
: "Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma." in: Biochemical and biophysical research communications, Vol. 485, Issue 4, pp. 713-719, (2017) (PubMed).
: "SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein-Dependent Apoptotic Pathway." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 13, pp. 3372-82, (2016) (PubMed).
: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).
: "SIRT6 expression is associated with poor prognosis and chemosensitivity in patients with non-small cell lung cancer." in: Journal of surgical oncology, Vol. 112, Issue 2, pp. 231-7, (2015) (PubMed).
: "Epigenetic modulation of chronic anxiety and pain by histone deacetylation." in: Molecular psychiatry, Vol. 20, Issue 10, pp. 1219-31, (2015) (PubMed).
: "Biochemical characterization of sirtuin 6 in the brain and its involvement in oxidative stress response." in: Neurochemical research, Vol. 40, Issue 1, pp. 59-69, (2015) (PubMed).
Synonyme und alternative Namen zu SIRT6
sirtuin 6 (Sirt6), sirtuin 6 (SIRT6), sirtuin 6 S homeolog (sirt6.S), sirtuin 6 (sirt6), 2810449N18Rik, AI043036, Sir2l6, SIR2L6, zgc:86729Bezeichner auf Proteinebene für SIRT6
- NAD-dependent deacetylase sirtuin-6
- NAD-dependent protein deacetylase sirtuin-6
- SIR2-like protein 6
- regulatory protein SIR2 homolog 6
- sir2-related protein type 6
- sirtuin type 6
- sirtuin (silent mating type information regulation 2 homolog) 6
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