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SIRT3 Produkte

(Sirtuin 3 (SIRT3))

Kategorien

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte SIRT3 Kategorien

SIRT3 Antikörper

High quality antibodies with extensive validation data.

SIRT3 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIRT3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SIRT3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (11)
  • (5)
Kat. Nr. ABIN390178
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN652184
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7435922
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SIRT3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970232
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6974831
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959491
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SIRT3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1320045
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125107
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320046
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SIRT3 Produkten

Nyárády, Turai, Funke, Györgyi, Makai, Prémusz, Bódis, Sulyok: "Effects of perinatal factors on sirtuin 3, 8-hydroxy-2'- deoxyguanosine, brain-derived neurotrophic factor and serotonin in cord blood and early breast milk: an observational study." in: International breastfeeding journal, Vol. 15, Issue 1, pp. 57, (2020) (PubMed).

Rezaei, Keshtzar, Khodayar, Javadipour: "SirT3 regulates diabetogenic effects caused by arsenic: An implication for mitochondrial complex II modification." in: Toxicology letters, Vol. 301, pp. 24-33, (2019) (PubMed).

Li, Chen, Yang, He, He, Xia, Zhang, Xiang: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).

Schwab, Sison, Meade, Broniowska, Corbett, Ebert: "Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons." in: Stem cell reports, Vol. 9, Issue 6, pp. 1839-1852, (2018) (PubMed).

Xu, Gao, Zhang, Wei, Chen, Dai, Zeng, Zhao: "SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 7296092, (2017) (PubMed).

Vidimar, Gius, Chakravarti, Bulun, Wei, Kim: "Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." in: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).

Chen, Liu, Li, Wang, Liu, Li, Zhang, Bu: "Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD." in: PLoS ONE, Vol. 10, Issue 3, pp. e0118909, (2015) (PubMed).

Takumida, Takumida, Katagiri, Anniko: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." in: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).

Wei, Zhou, Qiao, Ni, Li, You, Guo, Lu: "Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization." in: Cell death & disease, Vol. 6, pp. e1714, (2015) (PubMed).

Pfleger, He, Abdellatif: "Mitochondrial complex II is a source of the reserve respiratory capacity that is regulated by metabolic sensors and promotes cell survival." in: Cell death & disease, Vol. 6, pp. e1835, (2015) (PubMed).

Synonyme und alternative Namen zu SIRT3

sirtuin 3 (sirt3), sirtuin 3 (SIRT3), sirtuin 3 (Sirt3), 2310003L23Rik, AI848213, SIR2L3, Sir2l3, sirtuin, zgc:158774

Bezeichner auf Proteinebene für SIRT3

  • sirtuin 3
  • sirtuin
  • NAD-dependent deacetylase sirtuin-3, mitochondrial
  • NAD-dependent protein deacetylase sirtuin-3, mitochondrial
  • SIR2-like protein 3
  • mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
  • regulatory protein SIR2 homolog 3
  • silent mating type information regulation 2, S.cerevisiae, homolog 3
  • sir2-like 3
  • sirtuin type 3
  • SIRT3 mitochondrial
  • NAD-dependent deacetylase sirtuin-3
  • NAD-dependent protein deacetylase sirtuin-3
  • SIRT3L mitochondrial
  • mSIR2L3
  • mitochondrial protein lysine deacetylase
  • silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3
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