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SIRT1 Protein (AA 254-495) (His tag)

SIRT1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN5853631
  • Target Alle SIRT1 Proteine anzeigen
    SIRT1 (Sirtuin 1 (SIRT1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 254-495
    Spezies
    • 8
    • 4
    • 3
    • 1
    • 1
    Human
    Quelle
    • 7
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses SIRT1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMKK IIVLTGAGVS VSCGIPDFRS RDGIYARLAV DFPDLPDPQA MFDIEYFRKD PRPFFKFAKE IYPGQFQPSL CHKFIALSDK EGKLLRNYTQ NIDTLEQVAG IQRIIQCHGS FATASCLICK YKVDCEAVRG DIFNQVVPRC PRCPADEPLA IMKPEIVFFG ENLPEQFHRA MKYDKDEVDL LIVIGSSLKV RPVALIPSSI PHEVPQILIN REPLPHLHFD VELLGDCDVI INELCHRLGG
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SIRT1 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Denatured

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    SIRT1 (Sirtuin 1 (SIRT1))
    Andere Bezeichnung
    SIRT1 (SIRT1 Produkte)
    Synonyme
    sirtuin 1 Protein, AA673258 Protein, SIR2L1 Protein, Sir2 Protein, Sir2a Protein, Sir2alpha Protein, sir2l1 Protein, sirtuin Protein, SIR2 Protein, sirtuin 1 Protein, sirtuin 1 L homeolog Protein, SIRT1 Protein, SRT1 Protein, Sirt1 Protein, sirt1.L Protein
    Hintergrund
    SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. Alternative splicing results in multiple transcript variants. Recombinant human SIRT1 protein, fused to His-tag at N-terminus, was expressed in E.coli .
    Molekulargewicht
    31.6 kDa (280 aa)
    NCBI Accession
    NP_036370
    UniProt
    Q96EB6
    Pathways
    MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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