TLR7 Antikörper (Middle Region)

Produktnummer ABIN265146

Produktdetails anti-TLR7 Antikörper

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: This antibody detects TLR7. Located in the membrane, TLR7 is detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.

Aufreinigung: Purified

Immunogen: Peptide corresponding to 14 amino acids near the middle of mouse TLR7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5 to 2 μg/mL. Positive Control: Daudi Cell Lysate. Immunocytchemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Details zu TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Andere Bezeichnung: TLR7 (TLR7 Produkte)

Synonyme: TLR7-like antikoerper, RGD1563357 antikoerper, toll like receptor 7 antikoerper, toll-like receptor 7 antikoerper, TLR7 antikoerper, Tlr7 antikoerper

Hintergrund: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome (6) and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus (7). Activation of TLR7 by VSV results in stimulation of the immune response including IFNA secretion, suggesting the importance of TLR7 in virus recognition.Synonyms: Toll-like receptor 7

Gen-ID: 51284

NCBI Accession: NP_057646

UniProt: Q9NYK1

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades