CACNA1G Antikörper

Produktnummer ABIN265033

Produktdetails anti-CACNA1G Antikörper

Target: CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1G Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to CACNA1G.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the rat alpha1G calcium channel conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu CACNA1G

Target: CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Andere Bezeichnung: CACNA1G (CACNA1G Produkte)

Synonyme: CACNA1G antikoerper, cav3.1 antikoerper, ca(v)3.1 antikoerper, Ca(V)T.1 antikoerper, Cav3.1 antikoerper, NBR13 antikoerper, Cav3.1d antikoerper, [a]1G antikoerper, a1G antikoerper, alpha-1G antikoerper, mKIAA1123 antikoerper, Ca(v)3.1 antikoerper, calcium voltage-gated channel subunit alpha1 G antikoerper, calcium channel, voltage-dependent, T type, alpha 1G subunit antikoerper, calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog antikoerper, CACNA1G antikoerper, cacna1g antikoerper, cacna1g.L antikoerper, Cacna1g antikoerper

Hintergrund: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1g gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. alpha(1G) is most likely responsible for burst firing in thalamic relay cells. These neurons burst during various thalamocortical oscillations including absence seizures the modulation of the intrinsic firing pattern mediated by alpha(1G) T-type Ca(2+) channels plays a critical role in the genesis of absence seizures in the thalamocortical pathway.Synonyms: Cav3.1, Cav3.1c, KIAA1123, NBR13, Voltage-dependent T-type calcium channel subunit alpha-1G, Voltage-gated calcium channel subunit alpha Cav3.1

Gen-ID: 8913

NCBI Accession: NP_061496

UniProt: O43497