CACNA1G Antikörper (AA 901-1000)

Produktnummer ABIN680608

Produktdetails anti-CACNA1G Antikörper

Target: CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Bindungsspezifität: AA 901-1000

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1G Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Possible cross-reactivity with CACNA1H and CACNA1I

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CACNA1G/Cav31

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CACNA1G Antikörper (ABIN680608)

Lu, Long, Zhou, Xu, Hu, Li: "Mibefradil reduces blood glucose concentration in db/db mice." in: Clinics (São Paulo, Brazil), Vol. 69, Issue 1, pp. 61-7, (2014) (PubMed).

Details zu CACNA1G

Target: CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Andere Bezeichnung: CACNA1G (CACNA1G Produkte)

Synonyme: CACNA1G antikoerper, cav3.1 antikoerper, ca(v)3.1 antikoerper, Ca(V)T.1 antikoerper, Cav3.1 antikoerper, NBR13 antikoerper, Cav3.1d antikoerper, [a]1G antikoerper, a1G antikoerper, alpha-1G antikoerper, mKIAA1123 antikoerper, Ca(v)3.1 antikoerper, calcium voltage-gated channel subunit alpha1 G antikoerper, calcium channel, voltage-dependent, T type, alpha 1G subunit antikoerper, calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog antikoerper, CACNA1G antikoerper, cacna1g antikoerper, cacna1g.L antikoerper, Cacna1g antikoerper

Hintergrund:

Synonyms: NBR13, Cav3.1, Ca(V)T.1, Voltage-dependent T-type calcium channel subunit alpha-1G, Cav3.1c, Voltage-gated calcium channel subunit alpha Cav3.1, CACNA1G, KIAA1123

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

Gen-ID: 8913

UniProt: O43497