ErbB2/Her2 Antikörper (Extracellular Domain)
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- Target Alle ErbB2/Her2 Antikörper anzeigen
- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Bindungsspezifität
- AA 182-194, Extracellular Domain
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Reaktivität
- Human, Affe
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser ErbB2/Her2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Human ERBB2 / HER2. This antibody is expected to recognize both reported isoforms (NP_004439.2, NP_001005862.1). The immunizing peptide represents part of the extracellular domain.
- Aufreinigung
- Immunoaffinity purified
- Immunogen
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Synthetic peptide TLIDTNRSRACHP from an internal region of human ERBB2 / HER2 (NP_004439.2, NP_001005862.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%), Gibbon, Ferret, Panda, Horse (92%), Rat (77%), Mouse (69%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product ErbB2/Her2 Primärantikörper
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- Applikationshinweise
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Approved: IHC, IHC-P, Peptide-ELISA (1:128000)
Usage: Peptide ELISA: antibody detection limit dilution 1:128000. IHC: In paraffin embedded Human breast cancer shows cell membrane and cytoplasm staining in the affected cells of Her+ type and not in triple negative type. Recommended concentration, 4-6 μg/mL. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Tris saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Minimize freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
- Andere Bezeichnung
- ERBB2 / HER2 (ErbB2/Her2 Produkte)
- Synonyme
- CD340 antikoerper, HER-2 antikoerper, HER-2/neu antikoerper, HER2 antikoerper, MLN 19 antikoerper, NEU antikoerper, NGL antikoerper, TKR1 antikoerper, Erbb-2 antikoerper, Neu antikoerper, c-erbB2 antikoerper, c-neu antikoerper, mKIAA3023 antikoerper, wu:fv70f10 antikoerper, zgc:63601 antikoerper, erb2 antikoerper, erb-b2 receptor tyrosine kinase 2 antikoerper, ERBB2 antikoerper, Erbb2 antikoerper, erbb2 antikoerper
- Hintergrund
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Name/Gene ID: ERBB2
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: ERBB2, C-erb B2/neu protein, CD340, HER2, Herstatin, MLN 19, HER-2, Neu, NGL, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, CD340 antigen, MLN19, p185erbB2, TKR1 - Gen-ID
- 2064
- NCBI Accession
- NP_004439, NP_001005862
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
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