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SYK Antikörper (pTyr352)

SYK Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN2568466

Datenblatt (PDF)

Target Alle SYK Antikörper anzeigen

SYK (Spleen tyrosine Kinase (SYK))
Bindungsspezifität
29

22

19

16

10

10

8

8

8

7

6

6

5

5

4

4

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr352
Reaktivität
173

87

53

11

5

4

4

3

3

1

1
Human, Maus, Ratte
Wirt
156

22

3
Kaninchen
Passende Sekundärantikörper
Klonalität
159

21
Polyklonal
Konjugat
104

12

10

8

7

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
Dieser SYK Antikörper ist unkonjugiert
Applikation
147

83

46

25

22

18

14

14

12

8

4

3

3

2

2

2

1

1

1

1

1

1
Western Blotting (WB)

Spezifität

The antibody detects endogenous levels of SYK only when phosphorylated at tyrosine 352.

Aufreinigung

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen

SYK (phospho Tyr352) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 352 (S-P-Y (p)-A-D) derived from Human SYK.

Isotyp

IgG

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anti-Spleen tyrosine Kinase (SYK) (Internal Region) antibody
SYK Reaktivität: Human, Maus, Ratte WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibody
SYK Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (pTyr525) antibody
SYK Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (pTyr348) antibody
SYK Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibody
SYK Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 2G11E6 unconjugated

anti-Spleen tyrosine Kinase (SYK) (AA 387-417), (C-Term) antibody
SYK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB03097 unconjugated

anti-Spleen tyrosine Kinase (SYK) (pTyr525), (pTyr526) antibody
SYK Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibody
SYK Reaktivität: Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibody
SYK Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Western Blot: 1:500~1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store antibody at -20°C for up to one year.
Target

SYK (Spleen tyrosine Kinase (SYK))

Andere Bezeichnung

SYK (SYK Produkte)

Synonyme

p72-Syk antikoerper, Sykb antikoerper, p72syk antikoerper, spleen associated tyrosine kinase antikoerper, spleen tyrosine kinase antikoerper, syk antikoerper, SYK antikoerper, Syk antikoerper

Hintergrund

Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion

Molekulargewicht

72 kDa

Gen-ID

6850

NCBI Accession

NP_001167638

UniProt

P43405

Pathways

Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling