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SYK Produkte

(Spleen tyrosine Kinase (SYK))

Kategorien

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

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Ausgewählte SYK Kategorien

SYK Antikörper

High quality antibodies with extensive validation data.

SYK ELISA Kits

Reliable ELISA kits for a wide range of species.

SYK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SYK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p), IP, ICC
Validierungen
  • (4)
  • (6)
Kat. Nr. ABIN94475
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IF, IHC (p), IP, ICC
Validierungen
  • (9)
Kat. Nr. ABIN2854855
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Monkey, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (12)
Kat. Nr. ABIN6256708
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SYK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
  • (3)
Kat. Nr. ABIN1981728
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970412
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959691
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SYK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (2)
Kat. Nr. ABIN5570603
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321972
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321970
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SYK Produkten

Hasan, Rahman, Sebo, Osicka: "Distinct Spatiotemporal Distribution of Bacterial Toxin-Produced Cellular cAMP Differentially Inhibits Opsonophagocytic Signaling." in: Toxins, Vol. 11, Issue 6, (2020) (PubMed).

Zhang, Kang, Liu, Gu, Song, Li, Wang, Yao, Li, Li, Wang, Li, Mao: "Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase." in: Scientific reports, Vol. 10, Issue 1, pp. 439, (2020) (PubMed).

Schweig, Yao, Beaulieu-Abdelahad, Ait-Ghezala, Mouzon, Crawford, Mullan, Paris: "Alzheimer's disease pathological lesions activate the spleen tyrosine kinase." in: Acta neuropathologica communications, Vol. 5, Issue 1, pp. 69, (2018) (PubMed).

Köhler, Fuhr, Dinekov: "Distribution of spleen tyrosine kinase and tau phosphorylated at tyrosine 18 in a mouse model of tauopathy and in the human hippocampus." in: Brain research, Vol. 1677, pp. 1-13, (2018) (PubMed).

Greenblatt, Park, Oh, Kim, Shin, Lee, Lee, Singh, Lee, Hu, Xiao, Charles, Penninger, Lotinun, Baron, Ghosh, Shim: "CHMP5 controls bone turnover rates by dampening NF-?B activity in osteoclasts." in: The Journal of experimental medicine, Vol. 212, Issue 8, pp. 1283-301, (2015) (PubMed).

Nishikawa, Takahashi, Nakamori, Hosomi, Maruyama, Miyazaki, Izumi, Matsumoto: "The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments." in: Neuropathology and applied neurobiology, (2015) (PubMed).

Le Huu, Kimura, Date, Hamaguchi, Hasegawa, Hau, Fujimoto, Takehara, Matsushita: "Blockade of Syk ameliorates the development of murine sclerodermatous chronic graft-versus-host disease." in: Journal of dermatological science, Vol. 74, Issue 3, pp. 214-21, (2014) (PubMed).

Paris, Ait-Ghezala, Bachmeier, Laco, Beaulieu-Abdelahad, Lin, Jin, Crawford, Mullan: "The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation." in: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 33927-44, (2014) (PubMed).

Satoh, Tabunoki, Ishida, Yagishita, Jinnai, Futamura, Kobayashi, Toyoshima, Yoshioka, Enomoto, Arai, Saito, Arima: "Phosphorylated Syk expression is enhanced in Nasu-Hakola disease brains." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 32, Issue 2, pp. 149-57, (2012) (PubMed).

Coopman, Mueller: "The Syk tyrosine kinase: a new negative regulator in tumor growth and progression." in: Cancer letters, Vol. 241, Issue 2, pp. 159-73, (2006) (PubMed).

Synonyme und alternative Namen zu SYK

spleen associated tyrosine kinase (syk), spleen associated tyrosine kinase (SYK), spleen tyrosine kinase (Syk), spleen associated tyrosine kinase (Syk), p72-Syk, p72syk, Sykb

Bezeichner auf Proteinebene für SYK

  • Tyrosine-protein kinase SYK
  • tyrosine-protein kinase SYK
  • protein-tyrosine kinase
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