EPH Receptor A7 Antikörper (pTyr791)

Produktnummer ABIN2568103

Produktdetails anti-EPH Receptor A7 Antikörper

Target: EPH Receptor A7 (EPHA7)

Bindungsspezifität: pTyr791

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody detects endogenous levels of EPHA7only when phosphorylated at tyrosine 791.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: EPHA7 (phospho Tyr791) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y (p)-T-T) derived from Human EPHA7 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu EPH Receptor A7

Target: EPH Receptor A7 (EPHA7)

Andere Bezeichnung: EPHA7 (EPHA7 Produkte)

Synonyme: fc51g03 antikoerper, wu:fc51g03 antikoerper, si:dkey-23k6.1 antikoerper, EHK3 antikoerper, HEK11 antikoerper, Cek11 antikoerper, Ebk antikoerper, Ehk3 antikoerper, Hek11 antikoerper, Mdk1 antikoerper, CEPHA7 antikoerper, EPH receptor A7 antikoerper, eph receptor A7 antikoerper, ephrin type-B receptor 1-B antikoerper, Eph receptor A7 antikoerper, EPHA7 antikoerper, epha7 antikoerper, LOC100166161 antikoerper, Epha7 antikoerper

Hintergrund: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.

Molekulargewicht: 112 kDa

Gen-ID: 2045

NCBI Accession: NP_004431

UniProt: Q15375

Pathways: RTK Signalweg