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CCR5 Antikörper (pSer349)

CCR5 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2567085
  • Target Alle CCR5 Antikörper anzeigen
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Bindungsspezifität
    • 16
    • 13
    • 11
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer349
    Reaktivität
    • 154
    • 45
    • 39
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 102
    • 41
    • 20
    • 5
    • 4
    Kaninchen
    Klonalität
    • 105
    • 61
    • 3
    Polyklonal
    Konjugat
    • 83
    • 17
    • 12
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCR5 Antikörper ist unkonjugiert
    Applikation
    • 94
    • 71
    • 67
    • 22
    • 21
    • 18
    • 15
    • 14
    • 14
    • 13
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    The antibody detects endogenous levels of CCR5 only when phosphorylated at serine 349.
    Aufreinigung
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    Immunogen
    CCR5 (phospho Ser349) antibody was raised against a peptide sequence around phosphorylation site of Serine 349 (E-I-S (p)-V-G) derived from Human CCR5.
    Isotyp
    IgG
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  • Applikationshinweise
    Western Blot: 1:500~1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store antibody at -20°C for up to one year.
  • Target
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Andere Bezeichnung
    CCR5 (CCR5 Produkte)
    Synonyme
    CC-CKR-5 antikoerper, CCCKR5 antikoerper, CCR-5 antikoerper, CD195 antikoerper, CKR-5 antikoerper, CKR5 antikoerper, CMKBR5 antikoerper, IDDM22 antikoerper, Ckr5 antikoerper, Cmkbr5 antikoerper, CCR1-L antikoerper, GPCR antikoerper, CCR5 antikoerper, AM4-7 antikoerper, C-C motif chemokine receptor 5 (gene/pseudogene) antikoerper, chemokine (C-C motif) receptor 5 antikoerper, C-C motif chemokine receptor 5 antikoerper, CCR5 antikoerper, Ccr5 antikoerper
    Hintergrund
    Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
    Molekulargewicht
    40 kDa
    Gen-ID
    1234, 727797
    NCBI Accession
    NP_000570
    UniProt
    P51681
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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