PTPN13 Antikörper (AA 212-399)

Produktnummer ABIN2468004

Produktdetails anti-PTPN13 Antikörper

Target: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Bindungsspezifität: AA 212-399

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser PTPN13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Immunoaffinity Purified

Anwendungsinformationen

Applikationshinweise: Protein-tyrosine phosphatase antibody can be used for the detection of Protein-tyrosine phosphatase by Western Blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Konservierungsmittel: Without preservative

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: PTPN13 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Details zu PTPN13

Target: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Andere Bezeichnung: PTPN13 (PTPN13 Produkte)

Synonyme: FAP-1 antikoerper, PNP1 antikoerper, PTP-BAS antikoerper, PTP-BL antikoerper, PTP1E antikoerper, PTPL1 antikoerper, PTPLE antikoerper, hPTP1E antikoerper, PTPN13 antikoerper, AI324989 antikoerper, Ptpri antikoerper, RIP antikoerper, Ptp-bl antikoerper, ptp antikoerper, wu:fb50g04 antikoerper, zgc:162319 antikoerper, protein tyrosine phosphatase, non-receptor type 13 antikoerper, tyrosine-protein phosphatase non-receptor type 13 antikoerper, PTPN13 antikoerper, LOC100540743 antikoerper, ptpn13 antikoerper, Ptpn13 antikoerper

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as IkappaBalpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Molekulargewicht: 14.2 kDa (calculated)

Gen-ID: 5783

NCBI Accession: NP_006255

UniProt: Q12923