TFAP2A Antikörper

Produktnummer ABIN2463839

Produktdetails anti-TFAP2A Antikörper

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAP2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFAP2A.

Anwendungsinformationen

Applikationshinweise: TFAP2A antibody can be used for detection of TFAP2A by ELISA at 1:312500. TFAP2A antibody can be used for detection of TFAP2A by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TFAP2A antibody at -20 °C.

Details zu TFAP2A

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Andere Bezeichnung: TFAP2A (TFAP2A Produkte)

Synonyme: TFAP2A antikoerper, Ap-2 antikoerper, AP-2 antikoerper, AP-2alpha antikoerper, AP2TF antikoerper, BOFS antikoerper, TFAP2 antikoerper, ap2 antikoerper, xap2 antikoerper, XAP-2 antikoerper, ap2tf antikoerper, tfap2 antikoerper, ap-2alpha antikoerper, tfap2alpha antikoerper, cb93 antikoerper, fb83f04 antikoerper, fc31a07 antikoerper, wu:fb83f04 antikoerper, wu:fc31a07 antikoerper, tfap2a-a antikoerper, tcfap2a antikoerper, ap2a antikoerper, AP2alpha antikoerper, Ap2 antikoerper, Ap2tf antikoerper, Tcfap2a antikoerper, AP2 antikoerper, transcription factor AP-2 alpha antikoerper, transcription factor AP-2 antikoerper, tto transcription factor AP-2 alpha antikoerper, to transcription factor AP-2 alpha L homeolog antikoerper, to transcription factor AP-2 alpha S homeolog antikoerper, Transcription factor AP-2 alpha antikoerper, transcription factor AP-2, alpha antikoerper, TFAP2A antikoerper, LOC100302602 antikoerper, tfap2a antikoerper, tfap2a.L antikoerper, tfap2a.S antikoerper, ap2a antikoerper, Tfap2a antikoerper

Hintergrund: TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.

Molekulargewicht: 48 kDa

Gen-ID: 7020

NCBI Accession: NP_003211

UniProt: P05549

Pathways: Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism