BCL2A1 antibody can be used for detection of BCL2A1 by ELISA at 1:12500. BCL2A1 antibody can be used for detection of BCL2A1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store BCL2A1 antibody at -20 °C.
ACC-1 antikoerper, ACC-2 antikoerper, BCL2L5 antikoerper, BFL1 antikoerper, GRS antikoerper, HBPA1 antikoerper, Bcl2a1d antikoerper, BCL2A1 antikoerper, BCL2 related protein A1 antikoerper, BCL2-related protein A1 antikoerper, BCL2A1 antikoerper, Bcl2a1 antikoerper
Hintergrund
BCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.