BCL2A1 Antikörper (Middle Region)

Produktnummer ABIN950626

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BCL2A1 in WB, FACS, IHC (p) und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für BCL2A1 Antikörper (Middle Region) (ABIN950626)

Target: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-BCL2A1 Antikörper

Bindungsspezifität: AA 63-92, Middle Region

Spezifität: This antibody reacts to Bcl-2-like 5.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 63~92 amino acids from the Center region of human BCL2A1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BCL2A1

Target: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Hintergrund: Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.Synonyms: BCL2A1, BCL2L5, BFL1, Bcl-2-like protein 5, Bcl-2-related protein A1, GRS, HBPA1, Hemopoietic-specific early response protein, Protein BFL-1

Gen-ID: 597

NCBI Accession: NP_004040