TNFRSF18 Antikörper

Produktnummer ABIN2463662

Produktdetails anti-TNFRSF18 Antikörper

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF18 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFRSF18.

Anwendungsinformationen

Applikationshinweise: TNFRSF18 antibody can be used for detection of TNFRSF18 by ELISA at 1:312500. TNFRSF18 antibody can be used for detection of TNFRSF18 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TNFRSF18 antibody at -20 °C.

Details zu TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Andere Bezeichnung: TNFRSF18 (TNFRSF18 Produkte)

Synonyme: GITR antikoerper, TNFRSF18 antikoerper, AITR antikoerper, Gitr antikoerper, CD357 antikoerper, GITR-D antikoerper, TNF receptor superfamily member 18 antikoerper, tumor necrosis factor receptor superfamily, member 18 antikoerper, TNFRSF18 antikoerper, Tnfrsf18 antikoerper

Hintergrund: The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.

Molekulargewicht: 26 kDa

Gen-ID: 8784

NCBI Accession: NP_004186

UniProt: Q9Y5U5

Pathways: Cancer Immune Checkpoints