ING1 Antikörper

Produktnummer ABIN2463340

Produktdetails anti-ING1 Antikörper

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ING1.

Anwendungsinformationen

Applikationshinweise: ING1 antibody can be used for detection of ING1 by ELISA at 1:62500. ING1 antibody can be used for detection of ING1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ING1 antibody at -20 °C.

Details zu ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Andere Bezeichnung: ING1 (ING1 Produkte)

Synonyme: p24ING1c antikoerper, p33 antikoerper, p33ING1 antikoerper, p33ING1b antikoerper, p47 antikoerper, p47ING1a antikoerper, p33ING1c antikoerper, zgc:136918 antikoerper, ING1 antikoerper, 2610028J21Rik antikoerper, AA407184 antikoerper, AI875420 antikoerper, mING1h antikoerper, p33Ing1 antikoerper, p37Ing1b antikoerper, xing1 antikoerper, inhibitor of growth family member 1 antikoerper, inhibitor of growth family, member 1 antikoerper, inhibitor of growth family member 1 S homeolog antikoerper, ING1 antikoerper, Ing1 antikoerper, ing1 antikoerper, ing1.S antikoerper

Hintergrund: ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 32 kDa

Gen-ID: 3621

NCBI Accession: NP_937862

UniProt: Q5T9H0

Pathways: Protein targeting to Nucleus, Autophagie